Thanks for the info.  That's good to know.  I've been getting an understanding of what the differences were and its not immediately obvious why the Nevron UI couldn't be made to use the Client Profile.  Seems going forward the "Client Profile" is the recommended target.

Hi Brad,

It is not possible. .Net Framework 4 Client Profile does not support a lots of classes that we use.

Best Regards,
Nevron Support Team

I've noticed that its necessary to specify ".Net Framework 4" as your Visual Studio Target framework when using the Nevron UI.  I'd like to use ".Net Framework 4 Client Profile" instead.  Is this possible yet or a plan to support this?  I'm using the 11.1.17.12 version.